Search results for " phytochemical"

showing 10 items of 46 documents

Anthocyanins: Biosynthesis, Distribution, Ecological Role, and Use of Biostimulants to Increase Their Content in Plant Foods—A Review

2021

In the past century, plant biostimulants have been increasingly used in agriculture as innovative and sustainable practice. Plant biostimulants have been mainly investigated as potential agents able to mitigate abiotic stress. However, few information is available about their ability to influence fruit quality or change fruit phytochemical composition. In particular, very little is known about their effects on anthocyanin synthesis and accumulation. Due to the increasing demand of consumers for healthier foods with high nutraceutical values, this review tries to fill the gap between anthocyanin content and biostimulant application. Here, we elucidate the chemical structure, biosynthetic pat…

0106 biological sciencesDistribution (economics)antioxidant activityPlant ScienceBiologyPlant foods01 natural sciences03 medical and health scienceschemistry.chemical_compoundNutraceuticalBibliometric analysisSettore BIO/10 - BiochimicaSustainable agricultureSustainable practiceslcsh:Agriculture (General)030304 developmental biologynutraceuticals0303 health sciencesAbiotic stressbusiness.industryfungifruit qualityfood and beveragesphytochemicalslcsh:S1-972Biotechnologysustainable agricultureMeta-analysischemistryAgricultureAnthocyaninbusinessAnthocyanidins; Antioxidant activity; Bibliometric analysis; Fruit quality; Meta-analysis; Nutraceuticals; Phytochemicals; Sustainable agricultureAgronomy and Crop Scienceanthocyanidins010606 plant biology & botanyFood ScienceAgriculture
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Postharvest quality and sensory attributes of Ficus carica L

2017

The aim of this research was to evaluate the relationship between some physical and chemical characteristics and sensory descriptors of fig fruits ‘Dottato’ and ‘Melanzana’, belonging to the national germplasm bank of fig trees and cultivated in Southern Italy. The sensory principal descriptors used are external appearance, skin color, pulp color, odor, sweetness, stickiness, bitterness, juiciness, firmness, tannic taste and presence of achenes. Fresh weight, total soluble solids (TSS), titratable acidity (TA), TSS:TA, firmness, and sensory properties changed with cultivar. SSC was more correlated with sensory attributes than TA, but other factors may also be important in controlling this r…

0106 biological sciencesbiologymedia_common.quotation_subjectFicus04 agricultural and veterinary sciencesHorticulturebiology.organism_classification01 natural sciencesSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeHorticulturePostharvestQuality (business)Carica0405 other agricultural sciences‘Melanzana’ ‘Dottato’ fruit quality phytochemical characters fig fruit010606 plant biology & botany040502 food sciencemedia_common
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Indicaxanthin from Opuntia Ficus Indica (L. Mill) impairs melanoma cell proliferation, invasiveness, and tumor progression.

2018

Abstract Background: A strong, reciprocal crosstalk between inflammation and melanoma has rigorously been demonstrated in recent years, showing how crucial is a pro-inflammatory microenvironment to drive therapy resistance and metastasis. Purpose: We investigated on the effects of Indicaxanthin, a novel, anti-inflammatory and bioavailable phytochemical from Opuntia Ficus Indica fruits, against human melanoma both in vitro and in vivo. Study Design and Methods: The effects of indicaxanthin were evaluated against the proliferation of A375 human melanoma cell line and in a mice model of cutaneous melanoma. Cell proliferation was assessed by MTT assay, apoptosis by Annexin V-Fluorescein Isothio…

0301 basic medicine3003MaleSkin NeoplasmsPyridinesPyridinePhytochemicalsMelanoma ExperimentalPharmaceutical ScienceIndicaxanthinApoptosisBcl-2 B cell lymphoma gene-2 (Bcl-2)chemistry.chemical_compoundMice0302 clinical medicineOpuntia Ficus Indica (L.Mill)Settore BIO/10 - BiochimicaDrug DiscoveryCXCL1 chemokine (C-X-C motif) ligand 1MelanomaNF-κB nuclear factor kappa BMTT 3-[45-dimethyltiazol-2-yl]-25-diphenyl tetrazolium bromideMelanomaNF-kappa BOpuntiaComplementary and Alternative Medicine2708 DermatologyBetaxanthinsCXCL1030220 oncology & carcinogenesisMolecular MedicinePhC phytochemicalGrowth inhibitionIndicaxanthinHumanBiologyPhytochemicalNHEM normal human epidermal melanocyte03 medical and health sciencesc-FLIP FLICE-inhibitory proteinIn vivoCell Line TumormedicineAnimalsHumansNeoplasm InvasivenessSkin NeoplasmCell ProliferationNeoplasm InvasiveneInflammationPharmacologyCell growthAnimalDrug Discovery3003 Pharmaceutical ScienceApoptosimedicine.diseaseMice Inbred C57BL030104 developmental biologyComplementary and alternative medicinechemistryTumor progressionList of Abbrevations: AxV-FITC annexin V-fluorescein isothiocyanateBetaxanthinFruitCutaneous melanomaCancer researchPI propidium iodide PIPhytomedicine : international journal of phytotherapy and phytopharmacology
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Chemical–physical characteristics, polyphenolic content and total antioxidant activity of three Italian-grown pomegranate cultivars

2019

Background: In Mediterranean countries, there is an increasing demand for pomegranate fruits due to their antioxidant properties and nutritional values. The large diffusion of new genotypes and cultivars requires the knowledge of all fruit characteristics in connection with the cultivation area, to satisfy the market demand. This study seeks to determine the fruit quality attributes and nutraceutical values of three pomegranate cultivars (Wonderful, Acco and Kamel) grown in the Mediterranean climate. Methods: The fruits were evaluated for their main physico-chemical traits (weight, volume, height, width, thickness, total arils number, total arils weight, juiciness, fruit index, peel index a…

0301 basic medicineAntioxidantmedicine.medical_treatmentPunica granatum Fruit quality Antioxidant activity Phytochemical Physico-chemical characteristic Bioactive compound contentTitratable acidlcsh:TX341-641Biology03 medical and health scienceschemistry.chemical_compound0302 clinical medicineNutraceuticalArilSettore BIO/10 - BiochimicamedicineCultivar030109 nutrition & dieteticsNutrition and Dieteticslcsh:TP368-456food and beveragesSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeAntioxidant capacityHorticulturelcsh:Food processing and manufacturechemistryPolyphenolAnthocyanin030221 ophthalmology & optometrylcsh:Nutrition. Foods and food supplyFood Science
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Nutrigerontology: A key for achieving successful ageing and longevity

2016

During the last two centuries the average lifespan has increased at a rate of approximately 3 months/year in both sexes, hence oldest old people are becoming the population with the fastest growth in Western World. Although the average life expectancy is increasing dramatically, the healthy lifespan is not going at the same pace. This underscores the importance of studies on the prevention of age-related diseases, in order to satisfactorily decrease the medical, economic and social problems associated to advancing age, related to an increased number of individuals not autonomous and affected by invalidating pathologies. In particular, data from experimental studies in model organisms have c…

0301 basic medicineGerontologyAgingMediterranean dietNutrigerontologymedia_common.quotation_subjectAgeing; Longevity; Mediterranean Diet; Nutraceuticals; Nutrigerontology; Phytochemicals; Immunology; AgingPopulationLongevityPhytochemicalsImmunologyClinical nutritionBiologyPhytochemicalSocial issues03 medical and health sciences0302 clinical medicineNutraceuticaleducationmedia_commonSettore MED/04 - Patologia Generaleeducation.field_of_studyMediterranean DietLongevityAgeing030104 developmental biologyEditorialAgeingLife expectancyNutraceuticalNutraceuticals030217 neurology & neurosurgery
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Nutritional characterization of Butternut squash (Cucurbita moschata D.): Effect of variety (Ariel vs. Pluto) and farming type (conventional vs. orga…

2019

Farming systems and cultivar types are two of the main factors able to affect the nutritional quality of plant foods for human nutrition. Therefore, the aim of this study was to compare the impact of two unexplored variety (namely Ariel and Pluto) and farming type (conventional and organic) on physicochemical parameters, chemical and mineral composition, water- and fat-soluble vitamins, amino acid profile and antioxidant bioactive components of butternut squashes (Cucurbita moschata). In order to achieve this purpose, a multivariate statistical discrimination of the different parameters was carried out using the unsupervised principle component analysis (PCA). The most important differences…

030309 nutrition & dieteticsPhytochemicalsAntioxidants03 medical and health sciencesAntioxidant activity; Conventional-cultivars; Cucurbitaceae; Organic-cultivars; Phytochemicals0404 agricultural biotechnologyAntioxidant activityCucurbitaSettore AGR/13 - CHIMICA AGRARIAHumansNutsMagnesiumCultivarTocopherolFood scienceManganeseMinerals0303 health sciencesPlutobiologyChemistryOrganic-cultivarsSodiumConventional-cultivarsfood and beveragesAgriculture04 agricultural and veterinary sciencesbeta Carotenebiology.organism_classification040401 food scienceCucurbitaceaeZincHuman nutritionCucurbita moschataPotassiumOrganic farmingComposition (visual arts)Nutritive ValueCucurbitaceaeFood ScienceSquashFood Research International
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Toxicity as prime selection criterion among SARS-active herbal medications

2021

We present here a new selection criterion for prioritizing research on efficacious drugs for the fight against COVID-19: the relative toxicity versus safety of herbal medications, which were effective against SARS in the 2002/2003 epidemic. We rank these medicines according to their toxicity versus safety as basis for preferential rapid research on their potential in the treatment of COVID-19. The data demonstrate that from toxicological information nothing speaks against immediate investigation on, followed by rapid implementation of Lonicera japonica, Morus alba, Forsythia suspensa, and Codonopsis spec. for treatment of COVID-19 patients. Glycyrrhiza spec. and Panax ginseng are ranked in …

2019-20 coronavirus outbreakmedicine.medical_specialtyRelative toxicityCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pharmaceutical ScienceReviewSARS-CoV-2 severe acute respiratory syndrome coronavirus 203 medical and health sciencesCytochrome P450 Phytochemicals0302 clinical medicineSOD superoxide dismutaseDrug DiscoveryMedicineAnimalsHumansOral applicationIKK inhibitor of κB kinase030304 developmental biologyPharmacologyRational phytotherapy0303 health sciencesPublic healthCOVID-19 Coronavirus disease 2019JNK c-Jun N-terminale kinaseNO nitric oxidePlants MedicinalTraditional medicineToxicityACE2 angiotensin converting enzyme 2business.industrySARS-CoV-2Public healthCOVID-19Th2 T helper cells type 2NF-κB nuclear factor- κ B cellsComplementary and alternative medicine030220 oncology & carcinogenesisToxicityMolecular MedicineCYP cytochrome P450 monooxygenaseHIV-1 human immunodeficiency virus 1businessSelection criterionMAPK mitogen-activated protein kinaseDrugs Chinese HerbalPhytomedicine
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Content variability of bioactive secondary metabolites in Hypericum perforatum L

2021

Abstract St John’s Wort (Hypericum perforatum L.; Hypericaceae) is a perennial medicinal herb widespread and largely used in folk medicine inside the Mediterranean basin. Many bioactive compounds have been identified within its extracts. Under a pharmacological point of view, the most important of them belong to the chemical classes of naphthodianthrones, phloroglucinols and polyphenols. Many factors have been claimed responsible for the phytochemical variability in Hypericum perforatum, such as genotype, geographical origin, harvesting stage and age of the plants. Yet, when harvested plant material is addressed to the industry, the standardization of the active ingredients over cultivation…

AdhyperforinSt. john worthbiologyTraditional medicinephytochemical variabilitysecondary metabolitesHypericum perforatumPlant ScienceHypericaceaebiology.organism_classificationBiochemistryHypericinchemistry.chemical_compoundHyperforincultivationchemistryPhytochemicalPolyphenolHypericum perforatumCultivation Hypericum perforatum Phytochemical variability Secondary metabolites St John's WortHypericumAgronomy and Crop ScienceBiotechnology
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Distribution of betalain pigments in red blood cells after consumption of cactus pear fruits and increased resistance of the cells to ex vivo induced…

2005

Betalain pigments are bioavailable phytochemicals recently acknowledged as natural radical scavengers. This work, which extends previous research on the postabsorbitive fate of dietary betalains, investigated the distribution of betanin and indicaxanthin in red blood cells (RBCs) isolated from healthy volunteers (n = 8), before and during the 1-8 h interval after a cactus pear fruit meal, and the potential antioxidative activity of the pigments in these cells. A peak concentration of indicaxanthin (1.03 +/- 0.2 microM) was observed in RBCs isolated at 3 h after fruit feeding, whereas the concentration at 5 h was about half, and even smaller amounts were measured at 8 h. Indicaxanthin was no…

AdultCactaceaeMaleAntioxidantErythrocytesIndolesPyridinesmedicine.medical_treatmentBetalainsindicaxanthinred blood cellBiologyHemolysischemistry.chemical_compoundBetalainBotanymedicineHumansFood sciencecactus pear; betalains; betanin; indicaxanthin; red blood cell; oxidative hemolysis; bioavailable phytochemicalsBetaninbioavailable phytochemicalsbetaninbetalainGeneral Chemistrymedicine.diseaseHemolysisBetaxanthinsDietQuaternary Ammonium CompoundsRed blood celloxidative hemolysiKineticsmedicine.anatomical_structurechemistryCumene hydroperoxideFruitcactus pearFemaleBetacyaninsGeneral Agricultural and Biological SciencesIndicaxanthinEx vivoJournal of agricultural and food chemistry
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Healthy ageing and Mediterranean diet: A focus on hormetic phytochemicals

2021

Abstract Mediterranean diet (MedDiet) is rich in fruits and vegetables associated with longevity and a reduced risk of several age-related diseases. It is demonstrated that phytochemicals in these plant products enhance the positive effects of MedDiet by acting on the inflammatory state and reducing oxidative stress. Evidence support that these natural compounds act as hormetins, triggering one or more adaptive stress-response pathways at low doses. Activated stress-response pathways increase the expression of cytoprotective proteins and multiple genes that act as lifespan regulators, essential for the ageing process. In these ways, the hormetic response by phytochemicals such as resveratro…

AgingMediterranean dietmedia_common.quotation_subjectLongevityPhytochemicalsResveratrolBiologymedicine.disease_causeDiet MediterraneanHealthy Agingchemistry.chemical_compoundHormesisStress PhysiologicalMediterranean dietmedicineHumansFood sciencemedia_commonCellular stress-response pathwaysAgeing; Cellular stress-response pathways; Hormesis; Mediterranean diet; PhytochemicalsLow doseHormesisLongevityAgeingchemistryAgeingHealthy ageingOxidative stressDevelopmental Biology
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